For patients taking Semaglutide for weight loss due to obesity, or being overweight, it can be stopped when the benefits are no longer needed (weight loss goal is achieved). The amount of time it is taken, and the rate of weight loss varies from patient to patient. Many factors are involved – how much weight a patient has to lose, the dose required to produce the desired effects (appetite suppression and weight loss), etc. In clinical studies, patients lost 10-20% of their body weight (in a 200-pound person, that would be up to 40 pounds). The FDA recommends that the dosage of Semaglutide must be increased to its effective level of 2.4mg during the 16-20 weeks of therapy to include its weight loss benefits (please note, New Results generally see weight loss at lower doses, and our goal is to use the lowest dose possible to see the weight loss benefits.